Events Timeline

Timings Events
Sunday October 6th
3:00 – 5:00 pm Symposium Check-In/Registration
5:00 – 6:00 pm Opening Reception
6:00 – 8:30 pm Dinner

Dr. Karen Wilcox, PhD
Professor and Chair of Pharmacology and Toxicology, University of Utah
Welcoming Remarks

Dr. Ivan Soltesz, PhD
James R. Doty Professor of Neurosurgery and Neurosciences Stanford University
Keynote Address: "Organization and control of hippocampal networks in epilepsy."
Monday, October 7
7:30 – 8:30 am REGISTRATION
8:30 – 8:45 am Welcome, logistics and meeting goals
8:45 – 10:15 am Session 1: Biomarker Identification for Epilepsy

Session Chair: Misty Smith

Anchor Speaker: David Henshall, PhD
Professor of Molecular Physiology & Neuroscience RCSI Royal College of Surgeons in Ireland
"Circulating small noncoding RNAs as biomarkers of epilepsy."
Teresa Ravizza, PhD
Senior Researcher, Mario Negri Institute for Pharmacological Research
"Neuroinflammatory and behavioral biomarkers of epileptogenesis."
Gregory A. Worrell, MD, PhD
Professor and Chair, Division of Clinical Neurophysiology, The Mayo Clinic
"Integrating Brain Implants with Local and Distributed Computing Resources: A Next Generation Epilepsy Discovery & Management System.”"
Panel discussion
10:15 – 10:45 am Meet our Sponsors
10:45 – 11:15 am COFFEE BREAK
11:15 – 12:15 pm Session 2: Junior Investigator Career Panel

Chair: Amy Brooks-Kayal, MD, Professor of Pediatrics, Neurology, and Pharmaceutical Sciences, University of Colorado and Children’s Hospital Colorado
“We Want You (to do epilepsy research)!”
12:15 – 1:30 pm LUNCH
1:30 – 3:15 pm Session 3: Modern Imaging Approaches for Epilepsy Research

Session Chair: Cameron Metcalf

Anchor Speaker: Rafael Yuste, MD, PhD
Professor of Biological Sciences Columbia University
“Imaging epilepsy with single cell resolution.”
Kyle Lillis, PhD
Research Scientist, Instructor in Neurology Massachusetts General Hospital, Department of Neurology Child Neurology Division
“Imaging epileptogenesis with cellular resolution.”
Ukpong Eyo, PhD
Assistant Professor of Neuroscience, University of Virginia
“Microglia dynamics in response to seizures.”
Jing Liu, PhD
Postdoctoral fellow University of California, San Francisco
“Calcium imaging of network dynamics in a zebrafish model of epilepsy.”
Panel discussion
3:15 – 5:15 pm POSTER SESSION
Tuesday, October 8
7:30 – 8:30 am REGISTRATION
8:30 – 10:15 am Session 4: Cutting Edge Approaches to Gene Therapy & Optogenetics

Session Chair: Peter West

Anchor Speaker: Fabio Benfenatti, PhD
Center Director Istituto Italiano di Tecnologia
“Opto-epigenetic strategies for modulating brain plasticity and excitability.”
Lori L. Isom, PhD
Chair, Department of Pharmacology University of Michigan
“Targeted Augmentation of Nuclear Gene Output (TANGO): A novel therapeutic approach to treat SCN1A-linked Dravet Syndrome”
Esther Krook-Magnuson, PhD
Assistant Professor, Department of Neuroscience University of Minnesota
“Light-guided and automatic exploration of the hippobellum for seizure control.”
Melanie Tallent, PhD
Co-Founder and CSO LifeSplice Pharma
“Harnessing RNA splicing to treat neonatal epilepsies."
Panel discussion
10:15 – 10:45 am COFFEE BREAK
10:45 – 12:30 pm Session 5: Cerebral Organoids and Stem Cells in Epilepsy Research

Session Chair: Karen Wilcox

Anchor Speaker: Jack Parent, MD
William J Herdman Professor of Neurology University of Michigan Medical School
“New Models to Interrogate Genetic Epilepsies.”
Robert Hunt, PhD
Assistant Professor, Anatomy & Neurobiology University of California, Irvine
"Interneuron transplantation for the treatment of TBI"
Alex Shcheglovitov, PhD
Assistant Professor, Neurobiology and Anatomy University of Utah
“Modeling neurodevelopmental disorders with human cortical organoids.”
Cleber Trujillo, PhD
Associate Project Scientist University of California San Diego
“Applications of brain-model technology to study neurodevelopmental disorders.”
Panel discussion
12:30 – 2:00 pm LUNCH
2:00 – 3:45 pm Session 6: Drug Discovery Approaches for the Next Millennium

Session Chair: Scott Baraban

Anchor Speaker: Dr. Karen Wilcox, PhD
Professor and Chair of Pharmacology and Toxicology, University of Utah
“New Directions for the NINDS-Funded Epilepsy Therapy Screening Program.”
Stefanie Dedeurwaerdere PhD
Director, Neuroscience, UCB BioPharma
“Transcriptomics approaches identifying gene networks to guide drug discovery in epilepsy.”
Randy Peterson, PhD
Professor, Dean, College of Pharmacy, University of Utah
“Scaling up: screening for novel therapeutics using zebrafish.”
Dan Xu, Ph.D.
Research Assistant Professor, Northwestern University
“Novel Immunomodulatory Biodegradable Nanoparticles for the treatment of Dravet Syndrome.”
Panel discussion
3:45 – 4:15 pm COFFEE BREAK
4:15 – 6:00 pm Session 7: Zebrafish in Epilepsy Research & Drug Discovery

Session Chair: Cameron Metcalf

Anchor Speaker: Scott Baraban, PhD
William K. Bowes Jr. Endowed Chair in Neuroscience Research, University of California, San Francisco
“The Epilepsy Zebrafish Project (EZP) for Drug Discovery and Development.”
Manisha Patel, PhD
Professor, Department of Pharmaceutical Sciences, University of Colorado, Skaggs School of Pharmacy and Pharmaceutical Sciences
“Targeting metabolism in a zebrafish model of epilepsy.”
Burkhard Hoeckendorf, PhD
Research Specialist, HHMI’s Janelia Research Campus
“Optogenetic manipulation and whole brain calcium imaging of seizures in zebrafish.”
Éric Samarut, PhD
Senior Post Doctoral Researcher and Director of Business, Development chez Modelis Inc
“Modeling genetic epilepsies in zebrafish: from molecules to brain networks.”
Panel discussion
6:00 pm Closing Statements & Adjournment of Meeting